Helen H. Vogelbacker, Ph.D.

Education:

1977 - 1982 Ph.D., University of Pennsylvania
Major: Microbiology
1973 - 1977 B.S., Pennsylvania State University
Major: Microbiology

Experience:

1994 - Present Senior Scientist
Polyprobe Inc.
Philadelphia PA
Thor Nilsen, President
1989 - 1993 Research Associate
Department of Neurology
University- of Pennsylvania
Dr. John Kamholz
1988 - 1994 Staff Scientist Consultant
Biotechnology Training Institute
New Brunswick NJ
1988 - 1989 Research Associate
Department of Microbiology
University of Pennsylvania
Dr. Joseph Gols
1984 - 1988 Instructor
Department of Biology
University of Pennsylvania
1984 - 1986 Post-doctoral Fellow
Department of Surgical Research
University of Pennsylvania

Honors & Awards:

  • Research Fellowship, 1978 - 1981, N.I.H. Molecular and Cell Biology, University of Pennsylvania
  • Research Assistantship, 1977-1978, University of Pennsylvania
  • Graduated with Honors, Pennsylvania State University, 1977.

Publications:

  • Ling S., Vogelbacker H., Restifo L, Matson T., and Kozinski A.: Partial replication of ultraviolet (UV) irradiated T4 bacteriophange DNA results in amplification of specific genetic areas. J. Virol. 40: 403-410, 1981
  • Vogelbacker H., and Ling, S.: Evidences of the conversion of bromodeoxyuridine incorporated into T4 bacteriophage DNA to uracil; upon irradiation with UV (260 nm) and the biological consequences of this effect. Fed. Proc 40: (6) 1764, 1981
  • Restifo L. Vogelbacker It Ling S. Madera T., and Kozinski A.: The effects of UV-irradiation on the fate of 5-bromodeoxyuridine-labeled T4 bacteriophage DNA. J. Virol 47: 151-170, 1983
  • Kozinski A., Vogelbacker H., and Kozinski S.: In vivo replication and recombination of bacteriophage T4 DNA. Acta Microbiologica Polonica 35: 111-161, 1986
  • Flannigan K., Hennigan S., Vogelbacker H., Gots J., and Smith J.: Purine biosyntheses in Escherichia coli K-12; Structure and DNA sequence studies of The pur HD locus. Molecular Microbiology 4:381-392., 1990
  • Kamholz J., Sessa M., Scherer S., Vogelbacker H., Behrman T., Mokuno K., Baron P., Warbetz L.: Shy M., and Pleasure D.: Structure and expression of proteolipid protein in the peripheral nervous system J. Neurosci Res. 31: 231-244, 1992
  • Scherer S., Vogelbacker H., and Kamholz J.: Axons modulate the expression of proteolipid protein in the CNS. J. Neurosci Res. 32: 138-148. 1992
  • Feltri M., Scherer S., Nemni R-, Kamholz J., Vogelbacker R. S -wit M., Canal N., Quaranta V., and Wrabetz L.: Beta 4 integrin expression in myelinating Schwann cells is polarized developmentally regulated and axonally dependent. Development, 120(5). 1287-301, 1994
  • Vogelbacker H., Grayzel J., and Nilsen T.: Dendrimer Signal Enhancement for Detection of HIV Sequence Poster presentation @ The San Diego Conference; The Genetic Revolution, San Diego CA, 1994 Published in Clinical Chemistry, Vol. 40, No. 12, 1994
  • Nilsen.W., VogelbackerH.H., Getts R.C., Tian., Grayzel J.: Dendrimer Signal Enhancement in Blot Assays Poster presentation @ The American Association of Clinical Chemists national meeting, Chicago IL July 1996-, published in Clinical Chemistry 42(6)S202, 1996,
  • Vogelbacker H., Scherer S., and Kamholz J.: Altered patterns of myelin gene expression in tied rats, jimpy and shiverer mice. In preparation for Journal of Neuroscience Research .1997
  • Vogelbacker H., Getts R., Tian N., Labaczewski R., and Nilsen T.: DNA Dendrimers: Assemby and Signal Amplification. Presented @ American Chemical Society Meeting, April 1997

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Polyprobe ™ DNA Dendrimers and DNA Matrix Technology are covered under U.S. Patent No's 5,175,270 || 5,484,904, || 5,487,973 and patents pending.

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